Patient Derived Tumor Xenograft Models: Promise, Potential and Practice
Rajesh K. Uthamanthil, Peggy Tinkey, Elisa de Stanchina
Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory.
年:
2016
出版:
1
出版社:
Academic Press
语言:
english
页:
486
ISBN 10:
0128040106
ISBN 13:
9780128040102
文件:
PDF, 5.96 MB
IPFS:
,
english, 2016
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