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Stellate cells in health and disease

Stellate cells in health and disease

Chandrashekhar Gandhi PhD, Massimo Pinzani MD PhD FRCP
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Stellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs.

The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer.

Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain  sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology.

  • Presents coverage of the mechanisms of liver fibrosis with stellate cells as a target for therapy.
  • Shows stellate cells as a major participant in hepatic immunobiology, including transplantation immunology.
  • Key illustrations show the phenotypical changes in stellate cells in situ and tissue culture, their interactions with other cell types, signaling pathways and demonstrate the functions and roles of stellate cell in pathological processes.

种类:
年:
2015
出版:
1
出版社:
Academic Press
语言:
english
页:
335
ISBN 10:
0128005440
ISBN 13:
9780128005446
文件:
PDF, 10.34 MB
IPFS:
CID , CID Blake2b
english, 2015
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